SIRPA anticorps (C-Term) (PE-Cy5.5)

N° du produit ABIN888881

L’anticorps Lapin Polyclonal anti-SIRPA a été validé pour FACS. Il convient pour détecter SIRPA dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Porc, Cheval et Chien.

Aperçu rapide pour SIRPA anticorps (C-Term) (PE-Cy5.5) (ABIN888881)

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRPA est conjugé à/à la PE-Cy5.5

Application: Flow Cytometry (FACS)

Détail du produit anti-SIRPA anticorps (PE-Cy5.5)

Épitope: C-Term

Specificité: Excitation / Emission Wavelengths: 480,565,675nm/694nm

Réactivité croisée: Rat (Rattus), Souris, Lapin, Porc, Boeuf (Vache), Cheval

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogène: KLH conjugated synthetic peptide derived from human CD172a

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: -20 °C

Détails sur SIRPA

Antigène: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Autre désignation: SIRP Alpha

Sujet: Protein tyrosine phosphatases (PTPases) SHP1 and SHP2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPa (1),SHPS1 , MyD1, BIT and p84. SIRPa is a new gene family containing at least fifteen members. SIRPa is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP2. SIRPa has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.
Synonym: Signal regulatory protein alpha type 1, BIT, Brain Ig like molecule with tyrosine based activation motifs, Brain immunoglobulin like molecule with tyrosine based activation motifs, CD172 antigen like family member A, CD172a, CD172a antigen, Inhibitory receptor SHPS1, Macrophage fusion receptor, MFR, MYD 1, Myd 1, MYD1, p84,Protein tyrosine phosphatase non receptor type substrate 1, PTPNS1, SHP Substrate 1, SHPS1, Signal regulatory protein alpha 2, Signal regulatory protein alpha 3, Signal regulatory protein alpha, Signal Regulatory Protein Alpha Type 1, Signal regulatory protein alpha type 2, SIRP, SIRPA, SIRPalpha, SIRPalpha1, SIRPalpha2, SIRPalpha3, Tyrosine phosphatase SHP substrate 1, Tyrosine protein phosphatase non receptor type substrate 1, Tyrosine protein phosphatase non receptor type substrate.

Poids moléculaire: 56kDa

ID gène: 140885